A research team from University of the Basque Country is presently working on anti-inflammatory drugs, on the lines of working on analogues of the C1P molecule, which can have the potential of affecting healthy cells in a positive manner.
Presently, steroids and NSAIDs (Non-steroidal anti-inflammatory drugs) are the two drugs used for this purpose.
From Sciencedaily.com:
The team led by Antonio Gómez-Muñoz, from the Department of Biochemistry and Molecular Biology at the Science and Technology Faculty of the University of the Basque Country (UPV/EHU), is investigating alternatives to current anti-inflammatory drugs, creating synthetic analogues of the C1P (ceramide-1-phosphate) molecule. This molecule was discovered in 1990 in a case of human leukaemia. After synthesising it in the laboratory, it was observed that it was an important mytogenic agent (provoking cell growth and blocking the natural death of the cells). Moreover, it causes cell inflammation, i.e. when the cells detect the presence of this molecule, they secrete molecules that generate inflammation - prostaglandin and cytokine cells, for example.
The team of researchers inhibited inflammatory ability of the C1P molecule for ensuring its use as an effective anti-inflammatory drug to treat certain cell types without any negative effect on the other cells.
If you would like to make a comment, please fill out the form below.
